Bovine Dermal Fibroblasts (BDF)
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Bovine Dermal Fibroblasts (BDF)Bovine Dermal Fibroblasts (BDF)

Bovine Dermal Fibroblasts (BDF)

Bovine Primary Cells

Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies as they are one of easiest types of cells to grow in culture. Their durability also makes them amenable to a variety of manipulations ranging from studies employing gene transfection to microinjection. In general, fibroblasts secrete a non-rigid extracellular matrix which is rich in type I and/or type III collagen [1, 2]. Dermal fibroblasts have the ability to switch from a proliferative, migratory phase to a contractile, matrix-remodeling phase during wound healing. After injury, integrins, extracellular matrix, and cytokines can modulate fibroblast function in order to stimulate tissue repair [3]. Cultured Bovine Dermal Fibroblasts (BDF) are a useful in vitro model to study the mechanisms of wound healing and to develop therapeutic targets to reduce scarring and fibrosis. (SCB2300) (SCB2300)
Article number:SCB2300c
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Bovine Cell System
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