UP1 is a non-glycosylated secretoglobin family member protein which induces anti-inflammatory and anti-tumorigenic responses. The expression of Uteroglobin is induced by steroid hormones such as estrogen which is further enhanced by the non-steroid hormone prolactin. UP1 has been shown to induce growth stimulatory effects, sequester pro-inflammatory mediators and carcinogens and inhibit cell migration, cell invasion, platelet aggregation and T cell differentiation.
Product Name- Recombinant Human Uteroglobin (SCGB1A1)
Aliases- Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, Urine protein 1, UP1
Formulation- Lyophilized from a 0.2 µm filtered solution in PBS
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.