Neuritin is known to play an important role in promoting neuronal survival, differentiation, function, and repair. The expression of Neuritin can be induced in response to neural activity and neurotrophins. NRN1 promotes neurite outgrowth and arborization, especially branching of neuritic processes in primary hippocampal and cortical cells, suggesting its role in promoting neuritogenesis. Overexpression of NRN1 may be associated with astrocytoma progression. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.8 kDa polypeptide monomers.
Product Name- Recombinant Human Neuritin
Formulation- Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.