MMP-2 belongs to a family of endoproteases which need calcium and zinc in order to exert their catalytic capability (extracellular matrix remodeling). The elevated expression of these enzymes has been linked to many degenerative disorders, such as arthritis, cancer metastasis and skeletal growth-plate disorders. It has been shown that MMP-2 associates with many connective tissue cells as well as neutrophils, macrophages and monocytes.
Aliases- MMP-2, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, TBE-1
- Recombinant Human Matrix Metalloproteinase-2 µmMP2)
Formulation- Supplied as a 0.2 µm filtered solution in Tris, CaCl2, NaCl and Brij35
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.