IBP-7 is a secreted glycoprotein which mediates skeletal myogenesis by binding to IGF and inhibiting its ability to induce skeletal myoblast differentiation while maintaining a constant growth of myoblasts. It has been shown that IBP-7 suppresses growth of cancer cell lines through an IGF independent pathway.
Aliases- IBP-7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor, TAF, Angiomodulin, AGM
- Recombinant Human Insulin-Like Growth Factor Binding Protein 7 (IGFBP7)
Formulation- Lyophilized from a 0.2 µm filtered solution in PBS
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.