Concentration: 2 mg/mL heparin sodium salt (from porcine intestinal mucosa) in Dulbecco’s PhosphateBuffered Saline, sterile-filtered. Potency: > 180 Units per milligram*. *Units are USP (United States Pharmacopeia units) and indicate heparin potency by weight. Units are not evaluated by ScienCell but are provided by supplier.
Product Use: HEP is for research use only. It is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures.
Storage: Store at +4°C.
Shipping: Gel ice.
Caution: If handled improperly, some components of this product may present a health hazard. Take appropriate precautions when handling this product, including the wearing of protective clothing and eyewear. Dispose of properly.
References: [1] Bjork I and Lindahl U. (1982) “Mechanism of the anticoagulant action of heparin”. Mol Cell Biochem, 48(3):161-82.
[2] Rapraeger A, Krufka A and Olwin B. (1991) “Requirement of heparin sulfate for bFGF-mediated fibroblast growth and myoblast differentiation”. Science. 252(5013):1705-8.
[3] Roghani M, Mansukhani A, et al. (1994) “Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding”. J Biol Chem. 269(6):3976-84.
[4] Sasisekharan R, Ernst S and Venkataraman G. (1997) “On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans”. Angiogenesis, 1(1):45-54.