Human Pulmonary Artery Smooth Muscle Cells, Passage 1
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Human Pulmonary Artery Smooth Muscle Cells, Passage 1Human Pulmonary Artery Smooth Muscle Cells, Passage 1Human Pulmonary Artery Smooth Muscle Cells, Passage 1SC3110

Human Pulmonary Artery Smooth Muscle Cells, Passage 1

Cryopreserved Lung Primary Cells, Single Donor

Smooth muscle cells (SMC) are primary contributors to the development of arterial disease. The ability of vascular SMC to switch to a proliferative phenotype is one of the main factors in the development and progression of vascular disease. Pulmonary artery smooth muscle cells (PASMC) express VEGF and FGF-2 and are subjected to mechanical forces during pulsatile blood flow. Chronic lung hypoxia causes vascular remodeling with PASMC hyperplasia, and results in pulmonary hypertension [3]. Cultured PASMC play an important role in vascular disease research and can be used to identify new therapeutic targets to treat pulmonary vascular disease. (SC3110)
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