Human Esophageal Epithelial Cells, Passage 1
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Human Esophageal Epithelial Cells, Passage 1Human Esophageal Epithelial Cells, Passage 1

Human Esophageal Epithelial Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

The human esophagus is lined by a non-keratinizing, stratified squamous epithelium whose apical cell membranes and intercellular junctional complexes form a barrier against the influx of luminal content. The barrier helps to reduce exposure of surface cells to changes in osmolality, which occurs frequently within the esophageal lumen. Histologically, the esophageal epithelium consists of two zones, the basal and differentiated zones. Cellular proliferation is limited to the basal zone, and the cells are thought to migrate from this area towards the esophageal lumen. Migration is associated with the initiation of differentiation and the sequential expression of differentiation markers. Human esophageal epithelial cells (HEsEpiC) are an excellent in vitro model to study esophageal epithelium physiology and the mechanisms of esophageal carcinogenesis. (SC2720)
Article number:SC2720
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