Human Villous Mesenchymal Fibroblasts
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Human Villous Mesenchymal FibroblastsHuman Villous Mesenchymal FibroblastsHuman Villous Mesenchymal FibroblastsSC7130

Human Villous Mesenchymal Fibroblasts

Human Primary Cells

Fibroblasts are mesenchymal cells which are derived from the embryonic mesoderm. Since tissue-specific mesenchymal cells are essential for normal organ development, the villous mesenchymal fibroblasts (VMF) have been used as a model system for studying the cellular mechanisms involved in regulating human placental growth. The VMF lie directly beneath the villous basement membrane; they synthesize HGF, CSF-1, granulocyte CSF and IL-6 and play an important role in the regulation of trophoblast growth and function. Studies have shown that paracrine interaction between placental VMF and the cytotrophoblast in anchoring sites is required for stimulating trophoblast infiltration. (SC7130)
Article number:SC7130
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