Human Schwann cells are neural crest derivatives that ensheathe and myelinate axons of peripheral nerves. Each Schwann cell wraps around the shaft of an individual peripheral axon, forming myelin sheaths along segments of the axon.
Schwann cells play important roles in the development, function, and regeneration of peripheral nerves.
Human Schwann cells (HSC) are isolated from human spinal nerve. HSC are cryopreserved at passage one and delivered frozen.
Each vial contains 500 000 cells in 1 ml volume.
HSC are characterized by immunofluorescence with antibodies specific to S100.
HSC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi.
HSC are guaranteed to further expand for 10 population doublings under the conditions provided.
It is recommended to use Schwann Cell Medium (SCM, Cat. SC1701) for culturing HSC in vitro.
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.
HSC are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.