Renal glomerular endothelial cells (GEC) are a specialized microvascular cell type involved in the regulation of glomerular ultrafiltration. They form the inner part of the filtration barrier and are involved in pathophysiological processes in the glomerulum.
Renal glomerular endothelial cells can constitutively produce bio-active molecules, which can be amplified by inflammatory and thrombotic molecules.
Human Renal Glomerular Endothelial Cells (HRGEC) are isolated from human kidneys. HRGEC are cryopreserved after purification and delivered frozen.
Each vial contains 500 000 cells in 1 ml volume.
HRGEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and CD31 (PECAM), and by the formation of microtubular structures in vitro.
HRGEC are QA tested and found negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi.
HRGEC are guaranteed to expand beyond 10 population doublings under the conditions specified.
It is recommended to use Endothelial Cell Medium (ECM, Cat. SC1001) for the culturing of HRGEC in vitro.
HRGEC are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.