Human Coronary Artery Endothelial Cells, Passage 1
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Human Coronary Artery Endothelial Cells, Passage 1Human Coronary Artery Endothelial Cells, Passage 1Human Coronary Artery Endothelial Cells, Passage 1Human Coronary Artery Endothelial Cells, Passage 1

Human Coronary Artery Endothelial Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

The coronary arteries provide a substantial blood supply to meet the enormous energy demands of the heart for its constant contractile activity. Lining the vessel wall, coronary artery endothelial cells (CAEC) are continuously exposed to fluid shear stress that induces changes in cell morphology and the production of endothelium-derived substances regulating vasoconstriction and vessel growth. CAEC also modulate the expression of cellular adhesion molecules to control and fine-tune inflammatory responses and fibrinolysis. These physiological properties allow CAEC cultures to be widely used in the study of mechanisms for endothelium dysfunction, pathogenesis of coronary heart disease and atherosclerosis, and the development of novel disease treatments. (SC6020)
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