Human Cardiac Fibroblasts-fetal atrial
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Human Cardiac Fibroblasts-fetal atrialHuman Cardiac Fibroblasts-fetal atrialHuman Cardiac Fibroblasts-fetal atrialHuman Cardiac Fibroblasts-fetal atrial

Human Cardiac Fibroblasts-fetal atrial

Human Primary Cells

Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. CF proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis. CF cultures have been widely used as a model to study the cardiac matrix remodeling by physiological (exercise) and pathological (hypertension) stressors. CF also have been found to form electric coupling with myocytes through gap junctions exerting electrotonic influences on the cells. These electronic couplings are suggested to play an important role in genesis of complex fractionated atrial electrogram sites and thus are a perfect model for studying atrial fibrillation. (SC6340)
Article number:SC6340
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