Immortalized Human Lung Epithelial Cells (BEAS-2B-CSC 1196) were derived by infection of normal human bronchial epithelial cells with an adenovirus 12-simian virus 40 hybrid virus. These cells are non-tumorgenic. May be used for research in lung biology.
Immortalization Method: Immortalized with adenovirus12-simian virus 40 hybrid virus.
BioSafety Level: II
Organism: Human (H. sapiens)
Species: Human
Source Organs: Airway/Lung
Organ Type: Airway/Lung
Growth Properties: Adherent
Morphology: Epithelial
Propagation: TM044
Shipping Condition: Dry Ice
Storage Condition: liquid nitrogen or -180°C
Reference: Klein-Szanto, A. J., Iizasa, T., Momiki, S., Garcia-Palazzo, I., Caamano, J., Metcalf, R., Welsh, J., & Harris, C. C. (1992). A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells. Proceedings of the National Academy of Sciences of the United States of America, 89(15), 6693–6697. https://doi.org/10.1073/pnas.89.15.6693