The pituitary is a small, pea-sized gland located at the base of the brain. It is responsible for controlling and coordinating: 1) growth and development, 2) the function of various body organs, and 3) the function of other glandular organs. The study of pituitary gland development provides a remarkable example of cell specification. There are six major cell types of the anterior (endocrine) pituitary, and eight hormones: growth hormone, prolactin, thyrotrophin stimulating hormone, adrenocorticotrophic hormone, leutinizing hormone, follicle stimulating hormone, melanocyte stimulating hormone, and endorphin are produced by different pituitary cells, which are located in specific regions of the pituitary gland. Many pituitary cell types have been shown to express natriuretic peptide receptors and to respond to natriuretic peptides to stimulate cGMP accumulation [1].
Recommended Medium
It is recommended to use Epithelial Cell Medium (EpiCM, Cat. No. SC4101) for the culturing of RPC in vitro.
Product Use
This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Storage
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.
Shipping
Dry ice
Warranty
Cells are only warranted if ScienCell media and reagents are used and the recommended protocols are followed.
References
[1] Fowkes, RC, Forrest-Owen, W, and McArdle, CA (2000) C-type natriuretic peptide (CNP) effects in anterior pituitary cell lines: evidence for homologous desensitisation of CNP-stimulated cGMP accumulation in alpha T3-1 gonadotroph-derived cells