Mesenchymal stem cells (MSC) are a well-characterized population of adult stem cells. They have the potential to develop into mature cells that produce fat, cartilage, bone, tendons, and muscle [1, 2]. The developmental plasticity of MSC has generated tremendous interest because of the potential use of mesenchymal stem cells in regenerative medicine to replace damaged tissues. MSC cultured without serum in the presence of transformation growth factors will differentiate into chondrocytes. In contrast, MSC cultured in serum with ascorbic acid and dexamethasone will differentiate into osteoblasts. With their renewal capability, MSC have the potential to be transplanted into an injured site or seeded on a biomimetic scaffold to generate appropriate tissue constructs.
Recommended Medium
It is recommended to use Mesenchymal Stem Cell Medium (MSCM, Cat. no. SC7501) for culturing DMSC-ad in vitro.
Product Use
DMSC-ad are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.
Shipping
Dry ice.
References:
[1] Kassem M. (2004) “Mesenchymal stem cells: biological characteristics and potential clinical applications.” Cloning Stem Cells. 6: 369-74. [2] Barry FP, Murphy JM. (2004) “Mesenchymal stem cells: clinical applications and biological characterization.” Int J Biochem Cell Biol. 36: 568-84.