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In Vitro Tube Formation Assay

Cell based assay

Angiogenesis, or the formation of new blood vessels, plays an important role in many physiological (e.g.wound healing) and pathological (e.g. tumor growth and inflammation disease) processes. As a complex multi-step process, angiogenesis involves degradation of basement membrane, proliferation and migration of endothelial cells into extracellular matrix (ECM), followed by alignment and reorganization of endothelial cells into three-dimensional tubular structure and formation of new basement membrane. Specifically, the critical step of the formation of three-dimensional tubular structure by endothelial cells is the objective of many in vivo and in vitro angiogenesis assays to screen efficacy of both pro- and antiangiogenic agents. (SC8158)
Article number:SC8158
Stock status:Special Order Item
876,00 /
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