The Recombinant Norovirus Group-2 Capsid P-Domain,
E. coli derived, VA387 Strain contains a.a. from 225-520 having a Mw of 30 kDa. The protein is fused to a 6xHis-Tag at N-terminal and purified by chromatography techniques. P-domain (225-520 a.a.) forms P1- P2-P1 structure. P-domain has a receptor binding region to recognize human histo-blood group antigens (HBGAs). P-domain expressed in bacteria can spontaneously form a P dime and a P particle aggregated by 12 P dimmers. P-particle displays an enhanced binding activity to HBGAs higher than virus-like particle (VLP) formed by the full length capsid.
Formulation: Phosphate buffer and 17mM K2CO3.
Physical Appearance: Sterile Filtered clear solution.
Purity: Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Source:Escherichia coli.Stability: The Recombinant Norovirus Group-2 P-Domain although stable at +4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Transportation method: Shipped with Ice Packs.
Safety data sheet: Inquire at
info@3hbiomedical.com