HIV-1 gp120 CM Recombinant- is the external envelope protein, full-length 120 kDa, derived from the env. gene of HIV-1 and glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. The gp120CM stands for Chaing Mai from Clade E and is M-tropic meaning it binds to CCR5.Purified under conditions that maintain the tertiary structure of the molecule.
Formulation: 10mM Tris-Cl, pH 7.6, 150mM NaCl and 0.01% Triton N-101.
Physical Appearance: Sterile filtered colorless clear solution.
Purity: Greater than 90% as determined by HPLC analysis and SDS-PAGE.
Source: Baculovirus, Insect Cells.
Stability: Recombinant HIV -1 gp120 CM although stable at +4°C for 3 weeks, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Transportation method: Shipped with Ice Packs.
Uniprot ACC number: L03703
References: Title:Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability.Publication:Zhang X, Yu J, Kuzontkoski PM, Zhu W, Li DY, et al. (2012) Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability. PLoS Pathog 8(1): e1002461. doi:10.1371/journal.ppat.1002461Link:http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002461
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