MIG (CXCL9) protein belongs to the family of chemotactic cytokines known as chemokines. The synthesis of MIG is specifically induced in macrophages and in other cells by IFN-gamma.Human neutrophils produce mig in response to IFN-gamma in combination with either TNF-alpha or bacterial lipopolysaccharides and this response is blocked by IL-10 and IL-4. MIG is a chemoattractant for stimulated but not resting T cells, however it is not active on neutrophils or monocytes.
Product Name- Recombinant Human MIG (CXCL9)
Aliases- C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Monokine induced by interferon-gamma, µmall-inducible cytokine B9, µmK, HuMIG, SCYB9, CXCL9
Formulation- Lyophilized from 1.0 mg/mL solution in 25 µm NaCl 10 µm PB pH 7.0.
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.