The mucosa-associated epithelial chemokine CCL28 is a common mucosal chemokine which is constitutively expressed by epithelial cells in most mucosal sites. Both CCL28 and CCL25 have recently been shown to be essential for lymphocyte migration to gastrointestinal tissues. CCL28 attracts IgA ASC, but not IgG or IgM ASC, from both intestinal and extraintestinal mucosal tissue, while CCL25 preferentially attracts IgA ASC from the small intestine and its draining lymphoid tissues, as well as alpha-4-beta-7(+) T cells.
Product Name- Recombinant Human MEC (CCL28)
Aliases- C-C motif chemokine 28, CCL28, MEC, Protein CCK1, µmall-inducible cytokine A28, SCYA28
- Recombinant Human Mucosae-Associated Epithelial Chemokine (CCL28)
Formulation- Recombinant CCL-28 was lyophilized from PBS pH 7.4.
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.