Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Product Name- Recombinant Human IL28B (IFNL3)
Aliases- IL-28B, Interferon lambda-3, IFN-lambda-3, Cytokine Zcyto22, Interleukin-28C, IL-28C, ZCYTO22
- Recombinant Human Interleukin-28B (IFNL3)
Formulation- Recombinant Human Interleukin-28B was lyophilized from a 0.2 µm filtered PBS solution pH 7.4.
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.