Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
Product Name- Recombinant Human Eotaxin (CCL11)
Aliases- SCYA11, C-C motif chemokine 11, Eosinophil chemotactic protein, µmall-inducible cytokine A11
Formulation- Recombinant Eotaxin-1 was is lyophilized from as 0.2 µm filtered concentrated (1.0 mg/mL) PBS solution, pH 7.4.
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.