Platelet factor 4 (PF4/CXCL4) is an ELR− tetrameric, cationic chemokine that constitutes 25% of the protein in platelet alpha-granules. It is also found bound to the luminal vascular endothelial surface. Although platelets represent the primary source of PF4, it is also expressed at lower levels in other cells of the immune system including cultured T cells, monocytes, and endothelial and smooth muscle cells.
Product Name- Recombinant Human CXCL4 (PF4)
Aliases- C-X-C motif chemokine 4, Iroplact, Oncostatin-A, CXCL4, SCYB4
- Recombinant Human Platelet Factor 4 (PF4)
Formulation- Lyophilized from a 0.2 µm filtered solution containing 20 µm PBS,1.5 M NaCl pH 7.4
Endotoxin Level- <1.0 EU/µg of recombinant protein as determined by the LAL method.
Storage Condition- The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at +2° to +8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.