Recombinant human Thrombopoietin produced in CHO cells has a molecular weight range of 80-90 kDa due to glycosylation. The TPO is purified by proprietary chromatographic techniques.
Synonyms: MPL Ligand, THCYT1, MPLLG, TPO, ML, Thrombopoietin Nirs Variant 1, MKCSF, Thrombopoietin, Myeloproliferative Leukemia Virus Oncogene Ligand, Megakaryocyte Growth and Development Factor, Megakaryocyte Colony-Stimulating Factor, C-Mpl Ligand, MGDF, Megakaryocyte Stimulating Factor, Prepro-Thrombopoietin.
Formulation: TPO protein solution contains phosphate buffered saline (pH 7.4) and 2% albumin.
Physical Appearance: Sterile Filtered clear solution.
Purity: Greater than 98% as determined by SDS-PAGE.
Source: Chinese Hamster Ovary Cells.
Uniprot ACC number: P40225
Transportation method: Shipped with Ice Packs.
Stability: Thrombopoietin although stable at room temperature for 1 week, should be stored between 2-8°C.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of MO7e cells corresponding to a specific activity of 3x105 units/mg.
Safety data sheet: Inquire at info@3hbiomedical.com