Recombinant human IL-23 produced in HEK cells is a 55 kDa heterodimeric protein composed of 2 disulfide-linked subunits - 19 kDa (p19) and 43 kDa (p40).
Synonyms: Interleukin 23 Alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic Lymphocyte maturation factor 2 p40), NK cell stimulatory factor chain 2, Cytotoxic Lymphocyte maturation factor 40 kDa subunit, CLMF2, CLMF p40.
Formulation: IL-23 was lyophilized from a 0.1µm filtered solution (1.05mg/ml) containing 1xPBS.
Physical Appearance: IL-23 if supplied as a sterile filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 95% as determined by analysis by SDS-PAGE.
Source: HEK.
Uniprot ACC number: Q9NPF7
Transportation method: Shipped at room temperature.
Stability: Lyophilized Interleukin-23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-23 should be stored at +4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Biological Activity: The activity, as determined by the dose dependent secretion of IL-17 in response to IL-23 using murine splenocytes, the ED50 is 1.9 ng/ml.
Solubility: It is recommended to reconstitute the lyophilized IL23 in sterile 1xPBS containing 0.1% endotoxin-free recombinant HSA.
Safety data sheet: Inquire at info@3hbiomedical.com