GeneQuery™ Human PD-1/PD-L1 Checkpoint Pathway qPCR Array Kit

GeneQuery™ Human PD-1/PD-L1 Checkpoint Pathway qPCR Array Kit (GQH-PDI) is designed to facilitate gene expression profiling of 88 key genes involved in human PD-1/PD-L1 checkpoint pathway, and to help identifying potential prognostic biomarkers for cancer immunotherapy. 

PD-1/PD-L1 checkpoint pathway plays an important role in the maintenance of T cell stability, as well as mediating inhibitory signals for proliferation and function of T effector cells. PD-1/PD-L1 immune checkpoint blockade has resulted in enhancement of T cell immunity against tumors and viral pathogens. Brief examples of how genes may be grouped according to their functions are shown below:   

(8 controls in Bold and Italic)

Note: all gene names follow their official symbols by HGNC

* gene selection may be updated based on new research and development

This product is for laboratory research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.