The TO dye has a number of other desirable properties including:
- small size
- lack of toxicity
- plasma and nuclear membrane permeability
- short intracellular half-life
- the accessibility of a broad wavelength range simply via substitutions and alterations to the TO structure
TO1-biotin is the standard variety of TO dye for RNA Mango experiments; other dye variants are available. Learn more about the RNA Mango technology here.