Mesenchymal Stem Cell Osteogenic Differentiation Supplement (MODS) is a sterile, concentrated (100X) medium supplements designed for differentiation of primary mesenchymal stem cells (MSC) to an osteogenic lineage as determined by Alizarin Red staining in vitro. They are sterile, concentrated solutions that contain growth factors, hormones, and proteins necessary for MSC differentiation. The supplement is designed as additives for mesenchymal stem cell osteogenic differentiation medium (MODM, Cat. no. 7531) and should be used in conjunction with that medium.