Human Bronchial Smooth Muscle Cells, Passage 1
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Human Bronchial Smooth Muscle Cells, Passage 1Human Bronchial Smooth Muscle Cells, Passage 1Human Bronchial Smooth Muscle Cells, Passage 1SC3400

Human Bronchial Smooth Muscle Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

Airway smooth muscle is fundamental for maintaining airway tone. The specialized ultrastructural features and regulatory mechanisms of airway smooth muscle are vital for normal airway function. Patients with respiratory disorders, such as severe asthma, exhibit the distinguishing feature of increased bronchial smooth muscle mass. The increase in smooth muscle mass is related either to abnormal bronchial smooth muscle cell (BSMC) proliferation or the accumulation of contractile protein. Smooth muscle cell proliferation is an important component of airway remodeling in asthma and is consequently a target for the development of novel anti-asthma agents. Airway smooth muscle cells express CT-1 and release GM-CSF, RANTES and IL-8 in vitro. In order to develop therapies for asthma, researchers have utilized BSMC to elucidate the cellular and molecular echanisms underlying BSMC proliferation. (SC3400)
Article number:SC3400
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