Human Conjunctival Epithelial Cells, Passage 1
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Human Conjunctival Epithelial Cells, Passage 1Human Conjunctival Epithelial Cells, Passage 1

Human Conjunctival Epithelial Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

The conjunctiva is a translucent membrane that lines the inner surface of the eyelids and covers the sclera. It is overlaid by two layers of stratified, non-keratinized conjunctival epithelial cells (ConEpiC). ConEpiC can be distinguished from the corneal epithelium by a specific expression profile of keratins. ConEpiC is covered by mucin-rich glycocalyx, which promotes tear adherence, prevents pathogen penetrance, and provides lubrication. Decrease or loss of mucin/glycocalyx production generates squamous metaplasia, which may lead to dry eye and ocular surface diseases. ConEpiC also respond to histamine by stimulating phosphatidylinositol turnover and secreting cytokines, and as a result may be a good target when developing topical ocular drugs to treat allergic conjunctivitis. (SC6630)
Article number:SC6630
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