Human Sertoli Cells, Passage 1
(Click to display a larger image)
Human Sertoli Cells, Passage 1Human Sertoli Cells, Passage 1Human Sertoli Cells, Passage 1Human Sertoli Cells, Passage 1

Human Sertoli Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

Sertoli Cells (SerC) are essential for testicular development, spermatogenesis, and formation of the blood-testis barrier. SerC limit the passage of substances such as hormones and nutrients to the adluminal compartment of the seminiferous tubules. In addition to forming the blood-testis barrier, SerC also provide the main structural support for the seminiferous tubules and protect the germ cells from the immune system. Aberrant SerC proliferation can contribute to the development of male reproductive disorders such as testicular germ-cell cancer, cryptorchidism, hypospadias, and low sperm count. SerC proliferation is in part controlled by follicle-stimulating hormone (FSH) and thyroid hormone (TH), where FSH drives proliferation and TH promotes a more quiescent state. Cultured Human SerC are a useful in vitro model to better understand testicular dysgenesis syndrome and to develop treatments for male reproductive disorders. (SC4520)
Article number:SC4520
Unit:pcs
Stock status:Special Order Item
2.091,00€ / pcs
Qty:
Product Sheet
Print
Show large image
PDF
Back
Attached files

SC4520.pdf