Human Prostate Fibroblasts
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Human Prostate FibroblastsHuman Prostate Fibroblasts

Human Prostate Fibroblasts

Human Primary Cells

Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They have been extensively used for a wide range of cellular and molecular studies as they are one of easiest types of cells to grow in culture. Their durability also makes them amenable to a variety of manipulations ranging from studies employing gene transfection to microinjection. There is evidence showing that fibroblasts in various organs are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structural integrity of both healthy and healing soft tissue. Fibroblasts secrete a non-rigid extracellular matrix which is rich in type I and/or type III collagen. Cultured prostate fibroblasts synthesize FGF-like growth factors to stimulate their growth which may be a factor in the development of benign prostatic hyperplasia. (SC4430)
Article number:SC4430
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