Human Cardiac Fibroblasts - Juvenile ventricular
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Human Cardiac Fibroblasts - Juvenile ventricularHuman Cardiac Fibroblasts - Juvenile ventricularHuman Cardiac Fibroblasts - Juvenile ventricularSC6310Human Cardiac Fibroblasts - Juvenile ventricular

Human Cardiac Fibroblasts - Juvenile ventricular

Human Primary Cells

Cardiac fibroblasts (CF) provide structural support for cardiac myocytes and are responsible for extracellular matrix synthesis in the heart during growth and pathophysiological conditions. CF are an important cellular component of myocardial responses to injury and the source of paracrine growth factors. CF proliferation and synthesis of matrix is essential for scar formation at sites of myocardial infarction and cardiac fibrosis. CF have also been found to respond to mechanical loading to regulate the metabolic activity of ventricular cells, making them a good model to study the cardiac matrix remodeling using physiological (exercise) and pathological (hypertension) stressors. (SC6310)
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