The hypothalamus is a critical brain region linking the nervous and endocrine systems through the pituitary gland. The hypothalamus regulates vital homeostatic processes, including metabolism, bodily temperature, reproductive behaviors and food and water intake. Bovine hypothalamus extract (BHE) contains numerous growth factors and hormones that promote endothelial [1], epithelial [2, 3], and hybridoma cell proliferation [4], especially in low serum and serum-free media. This product is for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.