Human Pluripotent Stem Cell Cardiomyocyte Differentiation Kit, 2 x 50 ml
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Human Pluripotent Stem Cell Cardiomyocyte Differentiation Kit, 2 x 50 ml

Cell Culture Medium

Human pluripotent stem cells (hPSC), including embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC), possess the capability of differentiating into all derivatives of the three germ layers. Given that adult cardiomyocytes do not typically proliferate, hPSC can potentially provide an unlimited supply of cardiomyocytes. The cardiomyocytes derived from hPSC can be used for drug screening, toxicity testing, and developmental studies. The spontaneous cardiac differentiation of hPSC is inefficient, with less than 1 % of cardiomyocytes present in the culture. The differentiation process can be significantly enhanced by adding growth factors (BMP4, activin A, and FGF2 etc.), and small molecules, or using mouse END-2 cell-conditioned medium. The appropriate temporal addition of growth factors is also critic for cardiac differentiation. The Wnt signaling pathway is one of the key regulators in cardiac differentiation of hPSC. (SC5901)
Article number:SC5901
Unit:pcs
Stock status:Special Order Item
2.973,00 / pcs
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