The dermal papillae are a highly active group of cells derived from the dermis mesenchyme. Located at the base of the hair follicles, the dermal papillae play a crucial role in hair growth cycle by inducing follicle development from the epidermis to produce hair fiber.
Hair growth is tightly regulated by the epithelial-mesenchymal interaction of hair follicular cells, which involves various molecular pathways including BMP and Wnt signaling.
Human Hair Dermal Papilla Cells (HHDPC) are isolated from human scalp. HHDPC are cryopreserved at passage one and delivered frozen.
Each vial contains 500 000 cells in 1 ml volume.
HHDPC are characterized by their mesenchymal cell morphology and immunofluorescence with antibodies specific to fibronectin and CD105.
HHDPC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HHDPC are guaranteed to further expand for 5 population doublings under the conditions provided.
Recommended Medium
It is recommended to use Mesenchymal Stem Cell Medium (MSCM, Cat. no. SC7501) for culturing HHDPC in vitro.
Storage
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.
Shipping
Dry ice.
Product Use
The commercial product is a tool for in vitro laboratory science research use only. NOT for human or animal diagnostics, therapeutic, or other clinical uses. NOT for household, or other uses.