Renal proximal tubular epithelial cells (PTEpiC) play a crucial role in renal function. PTEpiC are located near injury sites in a variety of congenital, metabolic, and inflammatory diseases. PTEpiC can produce inflammatory mediators and actively participate in acute inflammatory processes by affecting and directing leukocyte chemotaxis via the production of IL-8. PTEpiC express IL-2R alpha and MHC class II antigens during inflammation, after renal transplantation, or in crescentic glomerulonephritis.
Human Renal Proximal Tubular Epithelial ( HRPTEpiC) Cells are isolated from human kidney. HRPTEpiC are cryopreserved at passage one and delivered frozen.
Each vial contains 500 000 cells in 1 ml volume.
HRPTEpiC are characterized by immunofluorescence with antibodies specific to cytokeratin-18 and/or cytokeratin-19.
HRPTEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRPTEpiC are guaranteed to further expand for 15 population doublings under the conditions provided.
Recommended Medium
It is recommended to use Epithelial Cell Medium (EpiCM, Cat. no. SC4101) for the culturing of HRPTEpiC in vitro.
Product Use
HRPTEpiC are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures.
Storage
Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments.
Shipping
Dry ice.