Ovarian Cell System

Here you can find ovarian endothelial cells, epithelial cells and fibroblasts. You can also find medium to grow the cells as well as RNA, DNA and protein derived from these cells.

The human ovary is covered with a single layer of flat to cuboidal surface epithelial cells (OSE). OSE are physiologically involved in follicular rupture and the subsequent repair of the follicle wall during reproductive age. OSE exhibit a gland formation in coculture with endometrial stromal cells in an estrogen-rich environment.

Angiogenesis is critical for many physiological processes including organ development and tissue repair. In human ovaries, angiogenesis is known to be associated with the development of follicles and the formation of the corpus luteum. A complex vascular network is formed within the thecal cell layer during follicular growth, and rapid neovascularization occurs toward the granulosa cell layer after ovulation.

Fibroblasts are mesenchymal cells derived from the embryonic mesoderm. They are one of easiest types of cells to grow in culture, and their durability makes them amenable to a wide variety of manipulations ranging from studies employing gene transfection to microinjection. There is good evidence that fibroblasts in different parts of the body are intrinsically different. Fibroblasts within tissues are exposed to a dynamic mechnical environment, which influences the structure integrity of both healthy and healing soft tissue.