Human Iris Pigment Epithelial Cells, Passage 1
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Human Iris Pigment Epithelial Cells, Passage 1Human Iris Pigment Epithelial Cells, Passage 1Human Iris Pigment Epithelial Cells, Passage 1SC6560

Human Iris Pigment Epithelial Cells, Passage 1

Cryopreserved Primary Cells, Single Donor

The iris is a pigmented disk with a variable aperture which controls the size of the pupil and the amount of light reaching the retina. It consists of the anterior limiting layer, the stroma, the dilator muscle layer, and the posterior pigmented epithelium. The iris pigment epithelial cells (IPEpiC) share the same embryonic origin as retinal pigment epithelial cells (RPE) and thus exhibit similar functional properties as RPE, including turnover of photoreceptors and synthesis of trophic factors. Previous studies showed that IPEpiC transplanted into the subretinal space inhibited abnormal neovascularization and photoreceptor degeneration, which suggests that IPEpiC transplantation may be used in the future to treat retinal disorders. (SC6560)
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